طب وعلوم

Parabiosis

Death

The rock that always destroys dreams and ambitions of many people.

 

But it’s also the reason why we keep going on as life is short and complicated.

 

Let’s forget about the philosophic part of the equation , as it has been an argument among philosophers  for centuries,  and  focus on the scientific part of the it.
Forensic medicine defines Death as: irreversible and permanent failure of respiratory, circulatory and nervous systems.

 

Death, as we all know ,is closer to old age groups.This is due do the fact that every cell of the body has certain age and certain capacity for performing  its function. Although we are  born with limited capacity and functions; it increases within  a certain time then declines again at a certain age.

 

The probable hypothesis about this is that our blood isn`t only formed out of RBCS, WBCS and platelet. It also contains:  hormones, molecules and messengers which work as factors that are responsible for the integrity of the human tissue ,but it has to also be noted that such  factors change by age into factors of aging.

 

Nevertheless,  there remains an urgent  question which is: what if we can reverse the process?; What if we are able to turn old people into young once again!Certainly  we aren’t going to use a time machine, although it sounds incredibly  amazing.

 

In the middle of 1800 ,Paul Burnett performed a very strange experiment at that time when he brought two rats; one was old and the other was younger, and made a common circulation between them through connecting their blood vessels together and the results were shocking.

 

On examining the old rat, Paul Burnett observed an improvement on the functions of its muscles , pancreas, liver, heart and the  brain  as well. It obviously  caused ” rejuvenation” which  means an  increase of  the number of stem cells and more efficacy of synapses and memory functions.The experiment was called Parabiosis.

 

Post to this experiment another one was performed by McCayin 1956 called Clive but the results were disappointing since  the rats used were kind of violent and one of  them killed the other.That is why he tended to tame both rats prior to performing the experiment a second time.

 

Afterwards, scientists at Stanford directed their research towards humans in order to check  if they could  use the same technique for curing aging- related diseases as Alzheimer’s and the results were kind of fair  and there were signs of recovery.

 

Scientists justifies this as “The blood of the youth has hormone working like factors that direct the stem cells to improve the function and efficacy of the target organ”.

 

But the whole attempt didn’t halt at such a stage as  a company located in the United States made use of the propaganda of the experiment.It sold the litter of youth plasma between age of 16 and 25 for 8000 dollar. However, things goes the other way of our will, since The  FDA didn`t approve of using  the blood of youth as a treatment  for aging-related diseases due to its side effects such as  allergic reactions, circulatory overload, lung injury, and infectious disease transmission.

 

Referrences :

https://www.nature.com/news/ageing-research-blood-to-blood-1.16762

https://medlineplus.gov/ency/article/004012.htm?fbclid=IwAR1a-_9kkTQQMD3fGoOhMJ1SazlxyFsPrWwWPp7OC2_H4lOq6Kh_GDdh4w8

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